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E L Saenko Selected Research

Factor VIII (Coagulation Factor VIII)

10/2004Molecular basis of haemophilia A.
8/2002Molecular defects in coagulation Factor VIII and their impact on Factor VIII function.
3/2002Factor VIII and transmissible spongiform encephalopathy: the case for safety.
1/2002Haemophilia A: effects of inhibitory antibodies on factor VIII functional interactions and approaches to prevent their action.
8/2001Catabolism of the coagulation factor VIII: can we prolong lifetime of f VIII in circulation?
6/2001Stable recombinant expression and characterization of the two haemophilic factor VIII variants C329S (CRM(-)) and G1948D (CRM(r)).
3/2001In hemophilia A and autoantibody inhibitor patients: the factor VIII A2 domain and light chain are most immunogenic.
2/2001Circulating factor VIII immune complexes in patients with type 2 acquired hemophilia A and protection from activated protein C-mediated proteolysis.

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E L Saenko Research Topics

Disease

12Hemophilia A (Haemophilia)
03/2008 - 02/2001
2Thrombosis (Thrombus)
01/2007 - 02/2005
1Hemorrhage
03/2002
1Prion Diseases (Transmissible Spongiform Encephalopathies)
03/2002

Drug/Important Bio-Agent (IBA)

8Factor VIII (Coagulation Factor VIII)IBA
10/2004 - 02/2001
4AntibodiesIBA
08/2002 - 02/2001
2Proteins (Proteins, Gene)FDA Link
10/2004 - 02/2001
2ThrombinFDA Link
03/2002 - 02/2001
1Blood Coagulation Factors (Coagulation Factor)IBA
03/2008
1Biocompatible Materials (Biomaterials)IBA
01/2007
1Thromboplastin (Tissue Factor)IBA
02/2005
1von Willebrand FactorIBA
08/2002
1Phospholipids (Phosphatides)FDA LinkGeneric
08/2002
1Complementary DNA (cDNA)IBA
06/2001
1AutoantibodiesIBA
03/2001
1Protein CIBA
02/2001
1Factor VIIIaIBA
02/2001
1Antigen-Antibody Complex (Immune Complex)IBA
02/2001

Therapy/Procedure

2Therapeutics
07/2006 - 08/2001